Toxicity profile of traditional herbal medicine journal of. British journal of pharmacology and toxicology 25, 251256. International journal of integrative sciences, innovation and technology 20. Hepatoprotective activity of some medicinal plants in sudan ncbi. Buy prickly poppy argemone mexicana herbal fire botanicals. Mexican prickly poppy is from the papaveraceae family and is native to mexico. The plant is pantropic in distribution and is a weed in waste places. Evaluation of hepatoprotective activity of argemone. It can grow up to one metre tall and contains a bright yellow juice latex that thickens the air as well as numerous alkaloids, whose effects have been used for a long time. The hepatoprotective activity of water and methanolic extracts of argemone mexicana l. Anxiolyticlike effect of ethanolic extract of argemone mexicana and its. Acetaminophen produced 100% mortality at a dose of 1 gkg in mice while pretreatment of animals with plant extract 500 mgkg reduced the death rate to 30%. Hepatoprotective activity of plant argemone mexicana linn against carbon tetrachloride ccl4 induced hepatotoxicity in rats. Rangasamy college of arts and science, tiruchengode 637215, tamilnadu, department of biochemistry, k.
From the cardiac department, universitycollege hospital, london. Mint has male antifertility activity mint, mentha arvensis linn. Pdf hepatoprotective activity of methanol extract of some. These results confirm the dosedependent property that characterizes the crude powdered leaf of argemone mexicana linn.
Evaluation of hepatoprotective activity of asparagus racemosus root against paracetamol induced acute liver injury in rats. Review article issn 22500480 vol 2issue 3julsept 2012 l 57 life science biotechnology. The synchronous activity of ingredients from polyherbal formulation is believed to be responsible for hepatoprotective activities of these formulations mention in table 5. Digital gene expression analysis provides insight into the. The methanol extracts of plant materials of some plants like casuarina equisetifolia, cajanus cajan, glycosmis pentaphylla, bixa orellana, argemone mexicana, physalis minima, caesalpinia bonduc, belonging to the different family were studied for hepatoprotective activity against swiss albino rats with liver damage induced by carbon tetrachlorideccl. This group also includes some related compounds with neutral or weakly acidic properties. Toxicity profile of traditional herbal medicine journal. Berberine and sanguinarine were equally distributed in roots and aerial tissues of developing plantlet whereas, in juvenile plants, sanguinarine was only detected in roots. Argemone mexicana papaveraceae, known as mexican poppy or.
Mar 19, 2018 berberine and sanguinarine alkaloids belong to a group of naturally occurring chemical compounds that mostly contain basic nitrogen atoms. Hepatoprotective activity of methanol extract of some medicinal plants against carbon tetrachlorideinduced hepatotoxicity in rats 305 using the standard microtechnique galigher and kozloff, 1976. Berberine and sanguinarine both are isoquinoline derivatives and. Hepatoprotective effects of the decoction and macerated. Antipyretic effect of argemone mexicana was studied by using yeast induced pyrexia method on mice. Retrospective analysis of concomitant cisplatin during. V, ragavendran p, sophia d, rajamanikandan s, sindhu t, durgapriya d and gopalakrishnan v. The present research was conducted in the laboratory to study the allelopathic effect of erythroxylum monogynum roxb. A lot of research has been envisaged to develop the better healing agents and it has been a challenging task to generate them and keep up the pace with problems encountered. Monographical study of biological properties of argemone. Pediatric drug reference drug indication pediatric dosage precautions comments lidocaine io pain 0.
The volunteer center of grant county elementary or middle school and work to install citytown. Argemone mexicana mexican pricklypoppy this plant can be weedy or invasive according to the authoritative sources noted below. It is in flower from june to august, and the seeds ripen from july to september. Hepatoprotective activities of two ethiopian medicinal. Hypoglycemic effects of citrullus colocynthis roots. However, there is little information about allelopathic effect of a. Argemone mexicana is native in mexico and the west indies, but has become pantropical after. Get a printable copy pdf file of the complete article 1.
Botanical occurrence, traditional uses, extraction. It is a pantropical spece with a long history of use in folk medicine since the aztecs period 1. Development of newly sanguinarine biosynthetic capacity in in. Thus, berberine 100 mgkg and stachyose 200 mgkg were used in the combination treatment, consistent with our previous study han et al. Rjpt evaluation of wound healing and anti microbial. Links vegaavila e, espejoserna a, alarconaguilar f, velazcolesama r 2009. The extracts were given at different doses, 100, 200, and 400. A comparative study of justicia adhatoda, mimosa pudica and vitex negundo against hepatoprotective activity in albino rats in vivo evaluation lisina k. Rjpt an update prominent wound healing property of.
Anxiolyticlike effect of ethanolic extract of argemone mexicana and. Preliminary phytochemical investigation and wound healing activity of the leaves of argemone mexicana linn. Monographycal survey of pharmacological potentials of. Rangasamy college of arts and science, tiruchengode. In vitro antibacterial potency of butea monosperma lam.
Agarwal v, sharma ak, upadhyay a, singh g, gupta r. Holistic psychopharmacology of fumaria indica fumitory. This is a pdf file of an unedited manuscript that has been accepted for publication. Papaveraceae mb patil, ss jalalpure, a ashraf indian drugsbombay. A boon to medicinal and pharmacological approaches in current scenario authors. Chemical constituents and biological activities of species. Allelopathic effects of argemone mexicana to growth of. Hepatoprotective activity of aqueous methanolic extracts of aerial parts of abutilon bidentatum on carbon tetra chloride ccl4 and paracetamol induced liver damage in rabbits. Naturally the investigative curiosity to promote the healing continues since ages. Berberinecontaining plants have been traditionally used in different parts of the world for the treatment of inflammatory disorders, skin diseases, wound healing, reducing fevers, affections of eyes, treatment of tumors, digestive and respiratory diseases, and microbial pathologies. To analyze berberine and sanguinarine biosynthetic capacities of both in vitro shoot and root cultures of argemone mexicana and tissues from entire plants at different developmental stages. Argemone mexicana is a pantropical weed with a long history of use in traditional medicine, dating back to the aztecs. Hepatoprotective activity of methanol extract of some.
Seed germination performance is one of the most essential development stages in medicinal and aromatic plants that may be unfavourably affected by the phytochemicals released from other plants in the soil environment. Argemone mexicana decoction versus artesunateamodiaquine for. Plants profile for argemone mexicana mexican pricklypoppy. Values of minimum inhibitory concentration mic and minimum bactericidal concentration mbc of leafextracts against each bacterium were obtained in a 96. Hepatoprotective activity of argemone mexicana aerial part extracts on ccl4 induced liver damage in wistar rats. Argemone mexicana prickly poppy is fast growing, very ornamental and covered with prickles. Neuropharmacological study of argemone mexicana linn.
Argemone argemos means white spot, eye cataract, which the plant was believed to cure. Papaveraceae is an herbal medicinal plant originated from mexico. Pdf this study is carried out on wistar rats to evaluate the hepatoprotective activity of argemone mexicana l aerial part extracts against ccl 4. Hepatoprotective activity was explored by testing the effect of sample drug against ccl 4induced liver injury in rats. Epidemic dropsy is caused by sanguinarine, an alkaloid constituent of several plants, including the mexican poppy, argemone mexicana figure 76.
Sitha institute of pharmaceutical sciences 2, hyderabad. Rhamnaceae had been the object of number of therapeutic indications in traditional medicine in the mediterranean area. Argemone mexicana prickly poppy, mexican pricklypoppy pfaf. Antidiabetic activity of aerial parts of argemone mexicana linn. Overall, ethanol has been found to be significant solvent for extraction of active plant substances, while methanol and chloroform were found to exhibit almost similar activities. Hepatoprotective activity of some medicinal plants in sudan. Aug 21, 2018 hepatoprotective activity of berberine is mediated by inhibition of tnf. Berberine and sanguinarine were equally distributed in roots and aerial tissues of developing plantlet whereas, in juvenile plants, sanguinarine was only detected in.
Strong larvicidal properties of argemone mexicana l. Development of newly sanguinarine biosynthetic capacity in. Many studies have showed a hepatoprotective activity of r. Due to their antioxidant activity, flavonoids and polyphenols are usually. Invitro antibacterial and antifungal properties of the. Other readers will always be interested in your opinion of the books youve read. The hepatoprotective activity of hydroalcoholic extract of the aerial part of c. Rangasamy college of arts and science, tiruchengode 637215, tamilnadu, india a. Argemone mexicana an overview sciencedirect topics.
Evaluation of the hepatoprotective activity of portulaca oleracea l. Hepatoprotective activity of melia azedarach leaf extract against simvastatin induced hepatotoxicity in rats. Retrospective analysis of concomitant cisplatin during radiation in patients aged 55 years or older for treatment of advanced cervical cancer a gynecologic oncology group study charles kunos, md, phd, chunqiao tian, phd. Argemone mexicana fruits extract using micronucleus assay in mouse bone marrow cells. Argemone mexicana, biological activity, papaveraceae. Dcfhtoxicatedcellswere recovered to about 100% with 100. Evaluation of hepatoprotective activity of argemone mexicana aerial part extracts on ccl 4 induced liver damage in wistar rats article pdf available november 2011 with 156 reads how we. Argemone mexicana is native in mexico and the west indies, but has become pantropical after accidental introduction or introduction as an ornamental. Medicinal plants used in mali for the treatment of. Antiulcer and antimicrobial activity of anogeissus latifolia. Cytotoxic activity of four mexican medicinal plants. The species is hermaphrodite has both male and female organs.
Histopathlogical studies further confirmed the hepatoprotective activity of 100 mgkg methanol extract. Our study intends to compare the hepatotoxic effects of two plant extracts especially two aqueous lyophilized extracts decocted and macerated. The mechanism of action of promising hepatoprotective therapies hepatoprotective agents, nutritional supplement, medicinal plants, herbal formulation is shown in figure 1. The present study is to monitor the anti microbial activity and wound healing activity of ethanolic extracts of stem, root and other parts of the plant argemone mexicana l belongs to the family papaveraceae. Nematicidal effect of the oil from the seeds of argemone mexicana. Mohammed ishaq 3 deccan school of pharmacy 1, hyderabad, andhra pradesh, india. The physicochemical properties of berberine contribute to the high diversity of extraction and detection. Argemone is from the greek argena, meaning cataract of the eye, and was the name used in the first century ad by the classical authors dioscorides ad 4090 and pliny ad 2379 for some spiny poppies, the juice of which was supposedly a cure for cataract. Argemone mexicana linn belonging to family papaveraceae is widely distributed. Silver city, new mexico the volunteer center uses a holistic strategy to end hunger in grant county that includes. Nov 11, 2016 to analyze berberine and sanguinarine biosynthetic capacities of both in vitro shoot and root cultures of argemone mexicana and tissues from entire plants at different developmental stages. The small, black, oily seeds of argemone resemble those of mustard and can become mixed with them accidentally or by deliberate adulteration. Fumaria indica is a medicinal plant of the fumitory family wildly growing throughout india.
Whether youve loved the book or not, if you give your honest and detailed thoughts then people will find new books that are right for them. Not needed in arrest situations midazolam seizure titrate in up to 1 mg increments iv up to 0. Flowering time is all rou nutritionally poor soil and also prefers acid, neutral and basic alkaline soils rastogi r. Albuquerque journal from albuquerque, new mexico on march 7. Consideringthe fact that the low oral bioavailability and poor intestinal absorption of berberine are key constraints of its clinical use, we.
The antibacterial activity of leafextracts was evaluated by the agarwell diffusion method against clinically isolated 12 grampositive and negative multidrug resistant mdr pathogenic bacteria in vitro. Bixa orellana, argemone mexicana, physalis minima, caesalpinia bonduc belonging to different family were studied for hepatoprotective activity against swiss albino rats with liver damage induced by cc14. The hepatic injury was achieved by injection of ccl 4 3 mlkg s. Cytotoxic activity of extracts from linum cell cultures. Plants used for the treatment of icterus jaundice in. In vivo assessment of antidiabetic and antioxidant activities of. Rangasamy college of arts and science, tiruchengode 637215, tamilnadu. Cyclea peltata cyclea peltata possess the potent diuretic activity. Prabhakaran v, srinivas ashok kumar b, sheshadri shekar d, nandeesh r, subramanyam p and ranganayakulu d. Nauclea latifolia and argemone mexicana, have been used in traditional medicine for the therapy of jaundice sourabie et al. Toxicological effects of berberine and sanguinarine frontiers. Alkaloids are produced by a large number of organisms including bacteria, fungi, plants, and animals.
Argemone mexicana papaveraceae is a prickly plant with intense yellow flowers like. Nnu21730 was upregulated as the stages progressed, and was expressed more highly. As a service to our customers we are providing this early version of the manuscript. Meanwhile, the other three ncss are closely related to t. Protective effect of ethanolic extract of tabernaemontana divaricata l. Alt is a sensitive indicator to acute liver damage and elevation of this enzyme in no hepatic disease is unusual. Sitha institute of pharmaceutical sciences 2, hyderabad, andhra pradesh, india. Argemone mexicana is known to have significant effects on cultivated agricultural fields. This plant may be known by one or more common names in different places, and some are listed above. The content is solely the responsibility of the author and is not necessarily endorsed by npcr.
The results of this study strongly indicated that aerial parts of a. Pdf evaluation of hepatoprotective activity of argemone. Argemone mexicana is a plant that grows in arid soils that are high in nitrates. The challenge is to use the information contained herein in meaningful ways to understand the conjunction of medical ethnography and the biology of therapeutic action.
Wound a clinical entity is as old as mankind, often possesses problems in clinical practice. Owning to these results, the plant has the potential to be used as a medicine against the diseases caused by free radicals. A boon to medicinal and pharmacological approaches in current scenario volume. Evaluation of the antiicterus effect of crude powdered. The enhanced wound healing activity may be attributed tothepresence ofsterols patil et ai, indian drugs, 2001,38,288293. Papaveraceae argemone mexicana papaveraceae, known as mexican poppy or mexican prickly poppy, is a species of poppy found in mexico and now in the united states, india, ethiopia and in other countries in africa. Argemone mexicana is an erect spiny annual or biennial herb, up to 1 m tall, with a slightly branched taproot. The expression of nnu21730 for the four stages in two cultivars differed from those of the other three genes figures 6be. The hepatoprotective activity of an aqueousmethanol extract of rubia cordifolia rubiaceae was investigated against acetaminophen and ccl 4 induced hepatic damage. Brine shrimp bioassay for biological activity of medicinal plants used in traditional medicines in tanzania.